The Premier League runners-up were dumped out of the European competition at the quarter-final stage after a shock 3-1 defeat to Lyon this month.
Zinchenko's wife Vlada Sedan is a sports reporter in Ukraine, who runs her own Youtube vlog.
And she said: “This is Guardiola's puncture. At such a crucial moment, making such an experimental tactic for City is a bummer.
"Perhaps I have no right to say this, perhaps Zinchenko will forbid me.
"But to put it mildly, and in order not to swear, this is completely Guardiola's fault."