Mourinho hopes his team can sail into the fifth round on Monday, but admits it will be a tough test.
He is an admirer of Wycombe boss Gareth Ainsworth, and expects a very tough game for his Premier League high flyers.
"I don't look at Wycombe as a team that is going to kill the giant," the Spurs boss told reporters.
"The Championship is one of the best leagues in the world. Better than the top leagues in many countries.
"With all respect to Marine, this is a different level."
"He must be a guy who enjoys life," said Mourinho said of his opposite number at Wycombe.
"He looks a happy guy and if to be happy, part of his life is to play the rock, to sing, to be part of the beautiful world that is music, he has to do it.
"I remember somebody was saying — or maybe he was saying it himself — that with a different haircut he would be seen as a great coach by others but I don't think it has anything to do with the haircut.
"Pep Guardiola has no haircut.
"My haircut is always the same, old-fashioned, white-hair haircut. He has this long, rock-star hair, amazing.
"And he is a good coach. You only stay in the club for so long if you are good — you are promoted, you stay and fight in a difficult competition like the Championship. He knows what he wants. He knows clearly the way he wants to play and how to get the very best out of his players.
"So he is a good coach. And a happy guy. I only feel sorry I cannot sing with him because I will destroy his music."