McArthur played a key role as Wigan Athletic upset City in the 2013 FA Cup Final and then helped produce another shock against the same side in the quarter-finals last season.
"It is a great experience when you play against a top team and win," he said. "I have been fortunate that the last two times I have played against them, I have won.
"Hopefully, that can continue. Chelsea have been the runaway side in the Premier League but City have got themselves back in the title race with some good results and they have looked good under Pellegrini. They will be dangerous but it is a great game to look forward to."