Manchester United forward Edinson Cavani may not be happy at possibly missing out on Uruguay's upcoming World Cup Qualifiers.

Cavani is known for his intense commitment to his country, but the Premier League has issued a statement saying no clubs will be releasing players to "red-list countries" during the upcoming international break.

A red-list country is one from where a person must quarantine if they come back to the UK, per COVID-19 rules and regulations.

Cavani reacted to the news by posting a picture of the news story on the Premier League website, along with an overlaid caption that stated "???"

Premier League Chief Executive Richard Masters said on the matter: "Premier League clubs have always supported their players' desires to represent their countries – this is a matter of pride for all concerned.

"However, clubs have reluctantly but rightly come to the conclusion that it would be entirely unreasonable to release players under these new circumstances. Quarantine requirements mean that players' welfare and fitness will be significantly impacted.

"We understand the challenges that exist in the international match calendar and remain open to workable solutions."