Two-goal Darron Gibson, Danny Welbeck, Gabriel Obertan and Ritchie de Laet all impressed against Harry Redknapp's team just six days after Sir Alex Ferguson's young crop were the subject of criticism following the 1-0 Champions League defeat at home to Besiktas.
And Neville, one of Manchester United's so-called 'golden' generation of youngsters who emerged in the early-1990s, insists that the club's new batch have already done enough to move beyond the stage of being unheralded rookies.
Neville said: "I don't think they should be called 'younger players.' Some of them are 19, 20, 21 years of age.
"Some of them are playing for their countries and they are all playing for United by right.
"The criticism they get is unfair at times, but they are playing for Manchester United and, when you lose a game, that's what happens.
"But they can hold their own at this level. They have quality and they shouldn't be regarded as young players.
"They are obviously developing, but they have the quality to play in the Premier League."