The 23-year-old was honoured at Football Writers' Association annual tribute awards.
Rashford became the youngest recipient of the FWA tribute in recognition of his work to fight child poverty in the UK.
"I would like to congratulate Marcus on his achievement and presentation (of the FWA Tribute Award) tonight," Ferguson said.
"I have known him since being a kid of 7 years of age, and seen him develop through the ranks of Manchester United into a truly wonderful person.
"Apart from his football life, what he has achieved in the last few months is quite astonishing, how he has helped the people in need is a truly amazing achievement.
"I would like to congratulate him on that. He has shown to young people in particular there is a different way of dealing with life.
"He has shown great humility, he has shown courage to do what he did, so this achievement is well deserved and should be recognised with what he has done.
"So Marcus, well done on a fantastic achievement."