Many in the game believe signing Dutchman Van de Beek is overkill at United.
But Berbatov told the Manchester Evening News: "I think that should be, even though it's a bit soon, that should be the favourite three in the middle of the park.
"Van de Beek in front of the defence and then you have Pogba and Fernandes. That would be a great, great midfield to watch.
"I never hid that I like (Scott) McTominay as well. I'd like to see him go back into the team because he is a young boy, he has great games as well, I'd like him to develop and become better and better.
"So hopefully he can be there as a back-up or maybe a starter, you never know. But this three you mentioned will be a great team to watch."