If they beat the winners of Tuesday night's tie between Wolves and Sevilla in the semis this weekend, United will play in the final in Cologne on August 21 - meaning they will have been there just short of two weeks.
Lindelof says the players are used to being confined while representing their national teams at the World Cup and other tournaments.
"It's going to be fine," he said. "I think all the players have been playing tournaments. I've been away playing the World Cup, the Euros and everything.
"Even if we're not able to leave the hotel at the moment, we have things to do there so I think it will be fine. No problem at all."
On victory over FC Copenhagen, he added: "We knew what kind of team they were and I think they made it difficult for us, even if we didn't play at our level.
"It's very difficult to say just why. It happens sometimes football. Of course, it's been a long season but we played a quarter-final in a European cup so I think everyone had to be ready for that.
"It happens sometimes in football that you don't perform at the level you want to. But the important thing is that we won and we're through to the semi-finals."