Manchester United have confirmed Anthony Martial and Luke Shaw will miss Saturday's clash with Southampton at St. Mary's.
The pair both sustained injuries in last weekend's loss to Crystal Palace.
Shaw injured his hamstring and is expected to miss a month of football, Martial's is less serious.
A club statement read: "Manchester United will be without Luke Shaw and Anthony Martial for the weekend encounter at Southampton in the Premier League.
"Both players were injured during the 2-1 defeat to Crystal Palace last Saturday and will be unavailable for Saturday's 12:30 BST kick-off at St Mary's."
