Manchester United boss Ralf Rangnick admits Edinson Cavani has suffered a new injury setback.

The striker reportedly suffered a calf problem which led to his withdrawal during the first half of Uruguay's World Cup qualifier against Chile.

In a separate interview with club media, Ralf replied to a question about his international players by saying: "Yeah, they all seem to be fit. The only player who is injured, unfortunately again, is Edinson Cavani. In his second game, he had to be substituted after 25 minutes with some calf problems.

"According to the doctor, he will be out for a couple of weeks, four weeks, maybe even five weeks. So we have to wait and see. That's obviously bad news to have another striker missing out. Apart from that, all the others seem to be fit."

Referring to the Brazilian pair Alex Telles and Fred, who also made long-haul trips, Rangnick added: "They flew back directly after the game. By today, they should have overcome any jet-lag problems and are available."