"Rio is coming along fine," he told MUTV. "He trained on Saturday and today with the other players who were also training. I think he's on course to play on Wednesday."
The only other question marks surround the fitness of Rafael and Wes Brown who both picked up minor knocks in the 1-0 win at the KC Stadium.
"I took Rafael off [as a precaution] and we'll get him checked on Monday, but hopefully he'll be okay," revealed Sir Alex.
"Wes got a little knock, but given that it was his first game back after so long out we're thankful he's come through well overall."