In the absence of Neymar and Edi Cavani, Mbappe will lead the PSG attack in the first-leg of their Champions League round 16 tie at Old Trafford.
Bernardo said of his former AS Monaco teammate: "Mbappé can be dangerous alone in attack.
"He is a very intelligent player, with speed, a big capacity to score. We can put him where we want.
"He can play right, left, in the centre."