Guardiola can't understand why Liverpool's current injury crisis has been treated more sympathetically than when City were struck down earlier in the season.
"I say to my players when you complain and look for excuses you cannot move forward," said Guardiola.
"Excuses is the worst thing in the world and in sport.
"Sometimes it is difficult for managers to finish games and five minutes later, give opinions about decisions into the microphone.
"But when you are relaxed in a press conference before a game, to say something to propose [provoke], I never did it or did it maybe once or twice for an exceptional reason, but not to propose [provoke].
"I am only concerned about the game, what we have to do to beat the opponents."
Guardiola has been criticised for setting up defensively on previous trips to Anfield - once using Ilkay Gundogan as a winger in a Champions League tie - but he insists the intention at kick off is always to win.
"Never ever in my career as a manager have I prepared to draw a game," he said.
"Sometimes it is not possible, the opponent is better so in the last 10 or 15 minutes it is better not to lose. But in the beginning, no way. Try to win the game.
"That is what we are going to do, always have done. Liverpool are the champions and I have no doubts we will see their best version, full of aggressivity and desire.
"It will be harder than ever so we have to be prepared and show enough courage to win the game."