The Citizens, who won the treble last season, have historically taken the League Cup seriously under Guardiola.
However, the Spanish boss reiterated that he is “not going to waste one percent of energy" of his first teamers.
“Some players who've had a lot of minutes are not going to play vs Newcastle," he said to reporters at the weekend.
“The Carabao Cup is great for all the guys who don't play regularly. They can play some minutes and that's perfect.
“But for the other players, I'm not going to waste one percent of energy for Carabao Cup. The likes of Kyle, Ruben playing 90 minutes for us, 90 minutes for the national teams, they are exhausted already.
“That's why we are going to play with the guys who need it, the academy, maybe me - my back is getting better so I might manage a few minutes!"