The ice-cool Belgian knows the champions need a calm front to lap up the red-hot atmosphere.
De Bruyne, 28, said: “You need to stay calm. If you get nervous and anxious, they smell it. It's kill or be killed.
“When Liverpool get that atmosphere, it gives them a nudge and for the other team, it gives a feeling of nervousness.
“If you are calm, collected and play maturely, sometimes you overcome it.
“That's the most difficult and important thing."