Origi, who is on loan from Liverpool this season, scored the opening goal in the 24th minute.
The goal occurred after the ball was stolen in Stuttgart's defensive half and fell to Origi. Origi then took the ball and shot it from just outside the box, between two defenders and past the goalkeeper's outstretched arms.
Stuttgart then equalised in the 60th minute through Mario Gómez.
Origi has now scored 5 goals in 23 games for Wolfsburg this season.
Origi's goal Vs @VfB#WOBVfBpic.twitter.com/EE965CgMQe
— Tom (@Wolfsburg__UK) February 3, 2018