Souness also suggested the striker's warm-up routine is partly to blame for some of the many injury problems he has endured over the years.
Sturridge started for yesterday's 3-2 win at Newcastle United.
"He's one of those boys who'll finish his career, look back and think 'I didn't make the most of what God gave me'," said Souness.
"I think he's wonderfully talented. Great touch. He might be a passenger tonight. When you have someone like him, so much ability, on a daily basis in training, you'd think 'why can't he have a pint of energy on match days?'"
Souness suggested Sturridge wouldn't have as many injury issues if he put more effort into his warm-up.
"I watched a game a few years ago, warming up, going through the motions in a warm up - no wonder you get injured when you come on as a sub," he said.
"I might be wrong, he might be a demon in training, but he's a man who's got so much ability, he'll finish his career and be angry with himself."