The Reds were left stunned after being held to a 1-1 draw by Lyon at the Stade Gerland on Wednesday evening.
"I am really disappointed because I think we played one of our best games of the season so far, but we did not get the result we wanted," Reina told Liverpoolfc.tv.
"I thought we'd done enough to win. We didn't deserve to lose at home when we played Lyon, and we didn't deserve to draw here, but that's the way it is and we have to face it.
"We were really unlucky but it's the way things are going at the moment. We have to keep fighting while we have a chance.
"At the moment we are not in the best situation, but I think we have a strong character and enough quality to sort things out.
"All we can do is play with desire and passion and try to be more consistent."