The two heavyweights go head to head in the Premier League this weekend.
It is a game that could have significant title implications, given Liverpool have a six point lead over champions City at present.
Keeper Ederson is a doubt for City, but Klopp believes the Brazilian will play.
"If he did not play, it would change [how City play]," Klopp said in an interview with Sky Sports.
"Ederson is an important part of their game, 100 per cent.
"Claudio Bravo can do similar things, but I expect Ederson to play 100 per cent.
"He's an ever-present player."