Klopp has confirmed Matip picked up a knock in Saturday's 1-0 victory at Sheffield United.
The centre-back completed the full 90 minutes alongside Virgil van Dijk at Bramall Lane, where the Reds chalked up their seventh win from seven Premier League matches this season.
Their only defeat of the campaign to date came at Napoli in their opening match of the defence of their Champions League crown last month, putting extra emphasis on Wednesday's visit of Red Bull Salzburg.
"In a good mood, good spirits, but we have to wait a little bit to give a final answer about fitness," he told the Liverpool website when asked about the condition of his squad.
“Joel Matip obviously got a slight knock at Sheffield, we have to see how exactly it will be.
“Apart from that, everybody should be fine. Of course, we have the players who weren't available last week – that means Shaq is still out; Alisson is very close but for sure not for tomorrow. I think that's it pretty much."