Mane returned to training last Monday after being given a 16-day break following Senegal's run to the African Cup of Nations final.
After losing that match, Mane wants to help his Liverpool team win some silverware in Istanbul on Wednesday.
"I think I am ready. Tiredness I think is here [pointing to his head]," he said at a news conference on the eve of Wednesday's match.
"For sure I have been playing for a long time. I don't think I've had a holiday of more than 20 days in seven years.
"I'm used to it. For sure, I'm ready. I'm here. Let's do it!"