Vardy has made the move as he stands by his wife Rebekah during her public falling out with Manchester United legend Rooney's wife Coleen.
Coleen accused Rebekah of leaking stories about her to the national press, something which Rebekah has furiously denied.
Although Vardy and Rooney are thought to have been good friends from back when they played together for England, the Foxes striker clearly feels that he cannot engage with Rooney while the row is still ongoing.
He has deleted Rooney as a friend on Instagram and also unfollowed him on Twitter.
A source told The Sun: “Jamie has always got on well with Wayne, but he won't stand for having his wife hung out to dry in public like this."