Leicester travel to Napoli on Thursday knowing a draw will be enough for a place in the last 32, while victory would give them a bye straight to the last 16, as group winners.
Vardy, who turns 35 next month, has been named among the substitutes for all five of Leicester's previous Europa League games as manager Brendan Rodgers aims to ensure he is fresh for the whole season.
Yet with Leicester determined to extend their stay in this competition, Rodgers is poised to turn to his top scorer, who has found the net nine times this term, while Youri Tielemans is also set to be involved, says the Daily Mail.
After 67 consecutive Premier League games for Leicester, Tielemans has not played since November 7 due to a calf injury but the Belgium midfielder resumed training last week and is likely to travel to Italy.
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