The Argentine has missed the tailed of Spurs' season due to a hamstring complaint.
Despite enduring a fragmented season, Lamela has declared himself fit to face Liverpool in Madrid on Saturday.
“I'm feeling good," said Lamela. “I still have a few more days to train after tomorrow to arrive in the best condition.
“We've prepared well. We've trained hard and we are ready mentally and physically. It's been good for the team.
“It's been a difficult [season]. When I pick up a new injury, with everything that I've lived through in my career now with the injuries, it's difficult. It's part of the game no? Sometimes it happens to me, sometimes to other players.
“I hope now to enjoy this game because it's like a present I've been given after such a difficult period I've been through. I'm preparing myself to give my best.
“The last two months I've finished the season with just the last two games and it's been hard. The last part of the season is the most important, no? But now it's an opportunity we need to take.
“We talk among ourselves that it's a great opportunity to be in the history of this club and that's what we want. We're trying to arrive in the best condition, the best feeling and I think I am confident we're going to play a very good game."