Liverpool boss Jurgen Klopp confirmed two of his centre-backs are injured.
The Reds had Virgil Van Dijk and defensive midfielder Fabinho playing in the heart of defence against Chelsea.
They emerged with a comfortable 2-0 win, but fans will be concerned about the new injury news to Joe Gomez and Joel Matip.
Speaking before the game, Klopp confirmed to Sky Sports: "Not a lot, but enough. Joe is not a real concern – it's probably only today. Same with Billy [Koumetio].
"With Joel, we have to see – it could take a few days longer. [It's] muscle. After injuries that's how it is. He looked perfect in the pre-season since he trained. But now he has got a little problem and we have to react, so that's how it is. That's why we start how we start."