The French midfielder was rested in the 3-0 win over Dynamo Kiev in the Champions League on Wednesday.
Ahead of the Derby della Mole, Rabiot said: “It will be a demanding and difficult match.
“They are in a difficult moment and winning would mean they'll restart.
“For us, on the other hand, it would be important to claim another win after the good performance in the Champions League."
He continued: “The history of this match means that, even without fans, it's a very important game, we must be careful, because they will try to win.
“In order to keep growing, we must win at all costs."