Jude Bellingham became the youngest English player in Champions League history as he started in Borussia Dortmund's 3-1 defeat at Lazio.
At 17 years and 113 days, the midfielder beat the record held by Phil Foden, who plays for Manchester City.
Dortmund were second best in Turin, with Ciro Immobile and a Marwin Hitz own goal giving the home side control.
Erling Braut Haaland gave Dortmund hope but Jean-Daniel Akpa Akpro responded almost immediately to seal Lazio's win.
The win represents a turn of fortune for Simone Inzaghi's side, who finished fourth in Serie A last season, but have only won one of their four league matches this season and were beaten 3-0 by Sampdoria on Saturday.