Hull's clash against Chelsea at Stamford Bridge on Sunday was marred by a horrific head injury suffered by Mason in head clash with Gary Cahill and it was revealed later that the Tigers midfielder had suffered a fracture on his skull.
Although Mason is currently in a stable condition following a successful surgery, the 25-year-old certainly will have a long recovery process before he makes a return to the pitch once again.
Ex-Barnsley striker Hume has also gone through a similar experience after fracturing his skull back in 2008 but he made a full recovery in eight months and the 33-year-old has now stated that Mason will be able to make a quick return as well.
Hume said: "My message to Ryan is to stay positive and surround himself with people who will support him.
"He will be fine and come back sooner than he thinks.
"Don't get me wrong, a fractured skull is a serious injury, but it does not have to be career-threatening.
"Ryan is still a young lad and will want to get back playing as soon as possible. He'll have a few mental barriers to clear but he's a strong character and I've no doubt he'll deal with them."