The Republic of Ireland international enjoyed several seasons across two spells at White Hart Lane, sandwiched between a failed stint at Liverpool, earlier in his career.
"The All Star game is a big occasion for the league and something you see over here in basketball, baseball and NFL. Every player in the MLS wants to be involved in this game," the 35 year old told Tottenham's official website.
"This is a special one for me because it's against Tottenham, my club, the club where I felt I made my name and had a big impact.
"Everyone knows Spurs is a club very close to my heart, so this is a big deal for me," the striker insisted.
Spurs will face the MLS All-Stars at Dick's Sporting Goods Park on Wednesday (2.15am UK time)