A key player in the Cottagers' Championship campaign, the 18-year-old was named on the bench for Saturday's win over Burnley.
And Jokanovic says it won't be the last game Sessegnon will sit out from this season.
"Ryan Sessegnon is 18 years old with around 100 games in professional football," he said ahead of Saturday's trip to Brighton.
"I made a decision, he does not need to play all of the games, nobody needs to play all of them.
"He is in the same process as the team, his potential is huge - 100 per cent he will be an important player for us this season.
"If he doesn't play a game or doesn't start a game it is not tragic news.
"He is working hard, he pushes forward and he will be an important part of our Premier League team."