Parker has also confirmed that winger Neeskens Kebano is out of the game
"[Joachim] Andersen has trained today, so we'll see how he goes and make a call," Parker said.
"He's progressed very well and that's a credit to the medical team. Terence Kongolo is still getting up to speed."
The manager also said, "I think it is, we are only six games in, but saying that, this is a big game for us.
"I think we all realise that scoring the first goal in this division is massive. History tells us that with this team and it is something we're working on."
Last season's 26-goal top scorer Aleksandar Mitrovic has so far scored twice from five league starts.
“I think we're playing to his strengths," said Parker. "What you can get away with last year you can't get away with this year."