The striker scored his first goal of the tournament in England's 3-0 last-16 win over Senegal, and Lloris said "very often he makes the difference".
"I only have positive things to say," said Lloris. "He's a very important player for the club and indeed for the England team as well.
"He's a real leader, an example for his team-mates and he is a top player. He's been decisive for his club and very often he makes the difference.
"Harry is known all over the world so I can't really add much. But he'll be an opponent. We'll both be representing our countries so our focus will be on that."
The two Spurs players could face each other in a penalty shootout should the game finish all-level and Lloris was asked about whether he would be confident against Kane because of their time together.
"You know better than me that Harry has the ability to shoot anywhere," said Lloris. "He's one of the best probably at this aspect of the game.
"Obviously for Harry or the other English players, they will be analysing their penalties. Then, it is all about feeling, all about instinct that you get during the match.
"Before you get to a penalty shootout, it is the time to make the difference on the pitch. We'll see. Anything can become decisive in what will be a big game.
"We have to be ready for every scenario."