Samuel's Range Rover was involved in a crash with a van at 7:55am in High Legh, Cheshire, after he had dropped his children off at school.
His family have been informed and are currently being supported by specially trained police officers.
The Trinidad and Tobago Football Association confirmed the devastating news on their official Facebook page.
Samuel had three children Javarne 10, Lakyle 8 and Amara 5 with wife Emma.
He had most recently been coaching Cheshire non-league side Egerton.