Premier League teams will be able to make five substitutions, rather than three, in each match to the end of the season after clubs approved new rules, reports BBC Sport.
Teams will also be able to name nine substitutes instead of the usual seven.
Football's international law-makers gave competitions the option of increasing substitutes to protect player welfare on the sport's resumption.
Premier League football will return on 17 June after a three-month absence.
Though teams can now make five substitutions, each will only have three opportunities to make changes throughout the match in order to minimise disruption to the game.