Five-time cup winners City advanced to the final eight with a convincing 5-2 victory over Championship side Huddersfield Town at the Etihad Stadium tonight to book their trip to the Riverside Stadium.
The two clubs have met once previously in the Premier League this season with Boro netting a late equaliser in a 1-1 draw at the Etihad.
Boro saluted 2-0 in their most recent FA Cup clash which came in the fourth round of the 2014/15 season.
2016/17 FA Cup - quarter-final schedule
March 11: Arsenal (PREM) v Lincoln City (NAT) - Emirates Stadium, London