The Blues will face Al Hilal after the Saudi Arabians' ruthless 6-1 demolition of Al Jazira.
Sunday's thrashing was the biggest winning margin in the history of the competition, with ex-Manchester United striker Ighalo netting on his debut for the club.
Ighalo only joined Al Hilal from fellow Saudi side Al Shabab in January, and he marked his first game with a goal against Emirati outfit Al Jazira.
He will now lead the line in Wednesday's semi-final after Chelsea jetted out to the UAE today to take part in the tournament.
Al Hilal did go 1-0 down initially, but Ighalo's effort and a goal from former West Brom man Matheus Pereira helped them come from behind to register the record-breaking win.