Pogba started yesterday's 0-0 draw with Chelsea on the bench.
"Paul Pogba should be on the pitch, this is a big, big game," Ince told beIN Sport.
"For him to be sitting on the bench and watching, with no disrespect, McTominay and Fred playing in his position, I would be saying 'I must be doing something wrong if I can't get in this team'.
"I know he has had an injury and he might be trying to bring him on a little later on.
"But I think it is time to move on. He has come out in the last two weeks and said he wants to join Real Madrid.
"I think his performances since he has been here have been inconsistent. Paul Pogba is a world class player and when he moved to Old Trafford I thought great.
"But all he has done is been a problem. The fans have gone against him and now Bruno Fernandes has come in and shown what you need to do to be a Man Utd player.
"He has performed consistently and Paul Pogba hasn't done that and that is why he finds himself on the bench."