The Toffees suffered an embarrassing home defeat at the hands of Norwich City on Saturday.
The loss leaves them in 15th on the table and Campbell says Silva should be held responsible.
"The writing's on the wall, you've got to be realistic and hold your hands up - if the project or plan ain't working then there's no harm in rejigging the plan," Kevin Campbell told Sky Sports News.
"Do you keep letting it hurtle towards the wall or do you redirect it and start making things happen?
"That's what the club ultimately going to have to do and it's going to take some strong leadership at the top and an element of ruthlessness.
"It's very difficult to come back from this and I don't see just how he's (Marco Silva) going to do it."