Howe is one of several names being linked with the Magpies, who parted ways with Steve Bruce this week.
Wilshere, who is currently a free agent, played under Howe at Bournemouth and would welcome linking up with him again.
Speaking to talkSPORT, Wilshere said of joining Toon with Howe at the helm: “I would love to. I'm not sure if he would take me though.
“I worked with him before and I still speak with him so I could ask the question.
“I think he'd be great with the players Newcastle have got. With the transition they're in, he could take them to the next level."
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