Mauricio Pochettino's side suffered an unexpected 1-0 defeat in the first leg in Belgium last week, but Nicholas thinks that Spurs will claim a comfortable 3-0 in the return leg at Wembley Stadium on Thursday.
He writes in his column for Sky Sports: "Tottenham were dreadful last Thursday but they found a way to bounce back against Fulham, which I thought was a dangerous tie.
"They've got Stoke at home on Sunday so I think he'll give a few more fringe players a chance than in the FA Cup, but Gent are an average team and I wouldn't be surprised if Spurs won 3-0, even with a few changes."
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