Everton lost 1-0 to Porto on Sunday in the Algarve Cup in Portugal.
The Toffees started the match with nine changes from their defeat to Lille on Saturday, with the same result.
Cenk Tosun came closest to scoring in the first half when he hit the post for Everton.
The Portuguese champions took the lead in 51st minute through Moussa Marega and held onto it until the final whistle.
The Liverpool side will next face Blackburn Rovers on Wednesday in their pre-season.
