Keane says that Everton will use their own target of finishing as high as possible to derail their neighbours' quest for a first league title in 29 years on Sunday.
"It's not the main reason we want to win the game - we want to win the game for ourselves," the centre-back told Sky Sports when asked if dashing Liverpool's hopes provides additional motivation.
"We're chasing seventh place ourselves, but in the back of our heads, if we can take points off Liverpool and get a win, that will dent their title chances which is great. That should make the fans happy.
"We want to put in a performance and we want to win the game, and we want the fans to be happy. If that's what they want, then that's what we want."