The 1-1 draw was overshadowed by Gomes' horrific injury in the second half - after he was challenged by Heung-min Son and collided with Serge Aurier.
Everton wrote in a statement: "Everton Football Club can confirm Andre Gomes will undergo surgery tomorrow (Monday, November 4) after sustaining an ankle injury in today's game with Tottenham Hotspur.
"The Portugal international was stretchered from the pitch during the second half of the game and taken straight to Aintree Hospital by ambulance accompanied by members of the Everton medical team. After undergoing hospital tests, it was confirmed he had suffered a fracture dislocation to his right ankle.
"The Club will provide further updates in due course."