Chelsea will meet Dynamo Kiev and Arsenal will face Rennes in the Europa League round of 16.
The two London clubs have been kept apart after the draw was held today.
The full draw is:
Chelsea v Dynamo Kiev
Eintracht Frankfurt v Inter Milan
Napoli v Salzburg
Valencia v Krasnodar
Sevilla v Slavia Prague
Zenit v Villarreal
Matches will be played on 7 and 14 March.