The 20-year-old, who has played as a left-back and a winger, joined Spurs from Fulham for £25m in August 2019 but has struggled to make an impact.
The Englishman has made 12 appearances for the Premier League club and had not featured during 2020-21.
Arsenal winger Reiss Nelson - Sessegnon's fellow England Under-21 international - had a successful loan spell with the German side during the 2018-19 season, making 29 appearances and scoring seven goals.
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