The Belgian has been in emphatic form this season, having provided eight Premier League assists.
But after limping off in Saturday's win over Everton, De Bruyne was not present at training on Monday.
He looks in doubt for Dinamo's visit to the Etihad due a groin issue, according to reports.
City will be looking to make it two from two in the competition after their opening game win over Shakhtar Donestk.
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