The champions have not yet given up on a third successive Premier League title but, as they trail leaders Liverpool by 11 points having played a game more.
Belgium international De Bruyne said: "We need to go game by game. We've dropped some points along the way but I think the reaction of the team has always been really good, the way we play has always been the same and we have played good football. This is the way to go forward.
"This is the way we have played four seasons with Pep Guardiola and this is not going to change.
"We work hard and we dedicate a lot to play well and if this is the way we play, people will enjoy it. We just try to win game by game and at the end of the season we will see what happens.
"If we don't win it we don't win it, but we work and play hard every day and this is the way to go forward."