Chile coach Reinaldo Rueda has confirmed reports Alexis Sanchez could miss up to three months due to an ankle injury.
And now it looks as though the 30-year-old could be out for "two or three months", should Inter decide to go ahead with surgery on the injury.
Speaking ahead of Chile' friendly against Guinea tomorrow, Rudea said: "We won't have Sanchez for this game.
"Should he undergo surgery with Inter, for two or three more months [he will be out].
"It's a shame, he was starting to play with his club, he scored two goals and played in the Champions League.
"We have to wait, the next few hours will be crucial as we will know what decision Inter will make. For us he is Alexis Sanchez, for Inter he is one of their players."