The German has won three and drawn one from his four games in charge.
Asked about his knowledge of the competition, Tuchel replied: "This would be huge, absolutely - the FA Cup is one of the most prestigious in the world.
"It is played at Wembley. Even if you were a little boy in Germany with no internet or no sports channels where you can watch every game like nowadays, you know the word 'Wembley' for sure and the words 'FA Cup'.
"You know this is a big, big game to play and a big goal to achieve."