The German confirmed that Andreas Christensen didn't suffer a concussion in the win at Barnsley, just a headache, while Timo Werner should be "absolutely OK" to come back into contention for their clash with Newcastle United.
Havertz is unlikely to recover in time for Monday's game and Thiago Silva is definitely out.
On summer signing Havertz, Tuchel said: "He is totally self-aware, very humble and super talented. I am convinced he will have a big future at this club."
On whether summer signing Havertz will produce the same form he showed at Bayer Leverkusen, he added: "I am pretty sure we will see it, there is no short answer though. What we know is there is all this potential in him and he can show it on the pitch. For every transfer, change of club, every player is different. Some players need more time to adapt, sometimes it is a process.
"All we can do is push him, support him and give him what he needs. He had a good start with us, good matches and I have a feeling that he is a guy who is clear, self-aware, humble and very talented. There are no doubts he will show this. Hopefully he can come back in the next days because I am confident he can have a big impact on this club."
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